Mechanisms of microRNA deregulation in human cancer
نویسندگان
چکیده
منابع مشابه
Mechanisms of MicroRNA Deregulation and MicroRNA Targets in Gastric Cancer.
Gastric cancer is a genetically heterogeneous disease that causes cancer-related deaths worldwide. Although many studies on this disease have been performed, the molecular mechanisms of gastric tumorigenesis, invasion, and metastasis have still not been identified. MicroRNAs (miRNAs) are endogenously coded small RNA molecules, 18-25 nucleotides in length, that regulate gene expression at the po...
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MicroRNAs are key regulators of various fundamental biological processes and, although representing only a small portion of the genome, they regulate a much larger population of target genes. Mature microRNAs (miRNAs) are single-stranded RNA molecules of 20-23 nucleotide (nt) length that control gene expression in many cellular processes. These molecules typically reduce the stability of mRNAs,...
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ژورنال
عنوان ژورنال: Cell Cycle
سال: 2008
ISSN: 1538-4101,1551-4005
DOI: 10.4161/cc.7.17.6597